Blue Jays vs Padres Prediction 5/20/25 MLB Picks Today

The San Diego Padres and the Toronto Blue Jays meet Tuesday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Blue Jays vs Padres Prediction.

Starting Pitching Matchup

The San Diego Padres will send out Dylan Cease for the start here, and Cease is 1-2 with a 4.60 ERA and 58 strikeouts this season. In his career, Cease is 1-0 with a 0.69 ERA and 18 strikeouts against the Blue Jays. Toronto did not have a starting pitcher announced at the time that this article was posted.


San Diego Padres Recap

The San Diego Padres come into this game looking to rebound from a 6-1 loss at the hands of the Seattle Mariners last time out to fall to 27-18 on the year. After this series, the Padres will head on the road for a series against the Atlanta Braves.

Padres Drop Three In A Row

Manny Machado has 52 hits, including a team-high 14 doubles and 7 stolen bases, while Fernando Tatis Jr. has 52 hits with a team-high 12 home runs and 27 RBIs, along with 8 stolen bases of his own this season. Luis Arraez has added 47 hits with 5 doubles, 2 triples, 3 home runs, and 15 RBIs, while Jackson Merrill’s added 29 hits with 4 home runs and 17 RBIs as well. Xander Bogaerts also has 9 doubles and 8 stolen bases this season. Gavin Sheets also has 7 doubles, 6 home runs, and 23 RBIs as well this season.

Why the San Diego Padres will win

San Diego Padres Player Prop Facts

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to bounce back from their 3-2 loss at the hands of the Tigers in Sunday’s rubber match to slip to 22-24 on the year. After this series, the Blue Jays will head on the road for a division series against the Tampa Bay Rays.

Blue Jays Drop Back-To-Back Series

George Springer has 36 hits and Bo Bichette has 57 hits, with Springer adding 5 home runs, a triple, 10 doubles, and 18 RBIs while Bichette has 15 doubles and 22 RBIs. Andres Gimenez has added 25 hits with 5 doubles and 3 home runs and 10 RBIs this season, along with 9 stolen bases, while Anthony Santander has 44 strikeouts so far this season. Vladimir Guerrero Jr. also has 5 homers, 8 doubles, and 20 RBIs, while Springer also has a .263 batting average and 43 strikeouts up to this point in the year.

Why the Toronto Blue Jays will win

Toronto Blue Jays Player Prop Facts

Total Runs Facts

Blue Jays vs Padres Prediction

I’m on the Padres in this one. I get the case to be made for the Blue Jays at home, but they didn’t look great against Detroit’s right-handers at home this past weekend. Dylan Cease has gotten back into the form of the Dylan Cease that we’ve come to expect in years past, who contended for Cy Young awards perennially. To me, this feels like a Padres spot, so give me San Diego behind another strong start from Cease.

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