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Phillies vs Cardinals Prediction 5/14/25 MLB Picks Today

St. Louis Cardinals (23-19) vs. Philadelphia Phillies (24-17)
May 14, 2025 1:05 pm EDT
The Line: Philadelphia Phillies -185 / St. Louis Cardinals 154; Over/Under: 8.5
(Get latest betting odds)

The St. Louis Cardinals and Philadelphia Phillies meet Wednesday in a MLB doubleheader at Citizens Bank Park. Here’s a Phillies vs Cardinals Prediction. This article will include a Phillies vs Cardinals Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 23-19 on the year and play the Royals, Tigers, and Diamondbacks next. The St. Louis Cardinals are batting .259 on the season, have a .336 OBP, and a .402 slugging percentage. The St. Louis Cardinals’ pitching staff has a 3.81 ERA and a 1.23 WHIP. Brendan Donovan leads the St. Louis Cardinals with 48 hits and 19 RBI, while Lars Nootbaar and Willson Contreras have combined for 79 hits and 45 RBI.

Erick Fedde and Sonny Gray will get the ball for the St. Louis Cardinals.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 24-17 on the year and play the Pirates, Rockies, and Athletics next. The Philadelphia Phillies are batting .257 on the season, have a .335 OBP, and a .400 slugging percentage. The Philadelphia Phillies’ pitching staff has a 3.75 ERA and a 1.24 WHIP. Trea Turner leads the Philadelphia Phillies with 49 hits and 14 RBI, while Nick Castellanos and Kyle Schwarber have combined for 84 hits and 53 RBI.

Jesus Luzardo and Aaron Nola will get the ball for the Philadelphia Phillies.

Why the Philadelphia Phillies will win

  • The Phillies have won each of their last 13 home games against National League opponents following a home loss.
  • The Cardinals have lost each of their last six day games against the Phillies following a win.
  • The Phillies have covered the run line in each of their last four home games against the Cardinals following a loss.
  • The Cardinals have failed to cover the run line in 16 of their last 19 road games against the Phillies following a win.
  • The Phillies have won the first inning in three of their last four day games at Citizens Bank Park.
  • The Phillies have led after 3 innings in four of their last five home day games.
  • The Phillies have led after 5 innings in five of their last six day games against NL Central opponents that held a winning record.

Why the St. Louis Cardinals will win

  • The Cardinals have won each of their last nine games.
  • The Phillies have lost seven of their last 10 games as home favorites on the first leg of a doubleheader.
  • The Cardinals have covered the run line in each of their last nine games.
  • The Phillies have failed to cover the run line in 11 of their last 13 games as home favorites on the first leg of a doubleheader.
  • The Cardinals have led after 5 innings in each of their last seven Wednesday games as underdogs.
  • The Cardinals have won the first inning in five of their last six games as road underdogs against National League opponents.
  • The Cardinals have led after 3 innings in five of their last six road games against NL East opponents.

Philadelphia Phillies Player Prop Facts

  • Kyle Schwarber has hit a home run in four of the Phillies’ last seven games as home favorites.
  • Bryce Harper has recorded at least one Double in four of his last five home appearances against the Cardinals after not playing the previous day.
  • J.T. Realmuto has recorded at least one RBI in each of his last seven Wednesday appearances at Citizens Bank Park.
  • Kyle Schwarber has scored a run in nine of the Phillies’ last 10 home games against opponents that held a winning record.
  • Jesus Luzardo has recorded six or more strikeouts in eight of his last nine appearances with his team as a home favorite against NL opponents.
  • Trea Turner has recorded at least one Single in each of the Phillies’ last eight games against NL opponents that held a winning record.
  • Nick Castellanos has recorded at least one hit in each of his last 11 appearances with his team as a home favorite against the Cardinals.
  • Kyle Schwarber ranks T1st in the league in Home Runs (14) this season.

St. Louis Cardinals Player Prop Facts

  • Willson Contreras has hit a home run in two of the Cardinals’ last three games as road underdogs.
  • Erick Fedde has recorded a win in three of his last four appearances against NL East opponents.
  • Masyn Winn has recorded at least one RBI in five of his last six road appearances after not playing the previous day.
  • Masyn Winn has scored at least one run in seven of his last eight road appearances after not playing the previous day.
  • Willson Contreras has recorded at least one Single in nine of the Cardinals’ last 10 games as underdogs against NL East opponents.
  • Erick Fedde has recorded five or more strikeouts in five of his last six appearances in day games against teams that held a winning record.
  • Willson Contreras has recorded at least one hit in each of the Cardinals’ last 11 games as underdogs against NL East opponents.
  • Victor Scott II ranks T7th in the league in Steals (11) this season.

Phillies vs Cardinals Prediction

Game 1 Prediction: The Phillies should be given the edge with Luzardo on the mound, but I have to lean toward the Cardinals and their nine-game winning streak. I’ve been riding with the Cards a lot over the last week, and it hasn’t run cold yet. Also, while Luzardo is dealing right now, Fedde has allowed 12 hits and three runs in his last 14 innings. Fedde has also posted a 3.00 ERA and .198 allowed batting average in 24 road innings. Give me the hot Cardinals.

Game 2 Prediction: Another spot where the Phillies are probably going to be favored, given the name on the mound. However, Nola hasn’t looked like himself this season, with a 4.89 ERA and .266 allowed batting average. In 17.1 home innings, Nola has a 4.67 ERA and a .290 allowed batting average. Gray has been sharper, with his 3.50 ERA and .229 allowed batting average. Also, the Cardinals haven’t lost since May 2. I’m going to roll with the Cardinals again until this hot streak runs cold.

Randy Chambers's Free Pick: Game 1: St. Louis Cardinals / Game 2: St. Louis Cardinals

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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